An increased risk of bleeding may occur when NSAIDs are used with agents that cause clinically significant thrombocytopenia, such as antithymocyte globulin.
Call your doctor right away if you have new or worsening joint pain, a skin rash that gets worse in sunlight, severe stomach pain, watery or bloody diarrhea, blood in your urine, or little or no urination.
Additive nephrotoxicity may occur with concurrent use of systemic bacitracin and other nephrotoxic agents, including salicylates.
Studies in animals have shown that, when given to the mother during pregnancy, these medicines can decrease the number of successful pregnancies and cause problems with bone development in the offspring.
Do not use this medicine during the later part of a pregnancy, unless your doctor tells you to.
This makes them slightly less effective in preventing pregnancy than are COCs.