Due to the inhibition of renal prostaglandins by NSAIDs, concurrent use with other nephrotoxic agents, such as gold compounds, may lead to additive nephrotoxicity.
It should be used with caution in patients with impaired renal function, electrolyte disorders, thyroid disorders, and acute coronary syndromes.
Although no instances of severe hematologic toxicity were seen in the premarketing experience with Anafranil, there have been postmarketing reports of leukopenia, agranulocytosis, thrombocytopenia, anemia, and pancytopenia in association with Anafranil use.
If stomach pain is severe you should see your doctor immediately as on rare occasions a tubal pregnancy could occur.
Tell your doctor right away if you become pregnant while taking this medicine.
If you think you could be pregnant while taking this pill you should stop taking it and consult your doctor immediately.